Wednesday Daily Piece: Vaccination Update for Adults Aged 65 and Older

Advisory Committee on Immunization Practices (ACIP) no longer recommends routine administration of pneumococcal 13-valent conjugate vaccine (PCV-13) in adults aged 65 and older. Rather, adults aged 65 and older are advised to engage with their healthcare provider in shared clinical decision making regarding PCV-13.

https://www.cdc.gov/vaccines/vpd/pneumo/hcp/PCV13-adults.html

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#PCV13 #ACIP #Immunizations

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Thursday’s Daily Piece: Insulin Storage Misconception

Did you know that it is a misconception that insulin must always be in the refrigerator or on ice? The truth is prior to first use an insulin vial or pen should be kept in the refrigerator. However, once it is opened and used, it can be kept a room temperature. So if you are going out to eat with friends or family, simply slide your insulin pen into your pocket or purse. Don’t miss out on fun outings simply because of insulin.

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#insulin #storage #misconception

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Tuesday’s Daily Piece: Tips for Navigating Thanksgiving Meal

Thanksgiving, annual day of giving thanks, is fast upon us. Many of us enjoy a meal with friends and family during Thanksgiving. Below are some practical tips to help you successfully navigate and enjoy this delicious meal.

If you are guest at a friend’s or family member’s home offer to bring a healthy dish with you so that you know you will be having at least one healthy option. 

If you are hosting the meal, clear the table after an adequate period of time and put away the food to avoid the temptation of guests grazing. 

If you are cooking, limit the sampling (or quality assurance, as I call it) of foods.

Make sure to have breakfast and snack earlier during the day to avoid any temptation to overindulge. 

Check out all of your food options first.  Consider how many servings of carbohydrates that you will select. One strategy is to take small spoonful’s of each food, or limiting your carbohydrates (i.e. potatoes, stuffing, dressing, rolls, desserts, rice) to two or three modest portions. Consider which carbohydrates that you truly want to eat.

Selecting fruits (in moderation) and non-starchy vegetables served raw, grilled or steamed are good options.  Limit the creams, butter, sauces and gravies.

Drink only low calorie beverages, water and unsweetened beverages. Limit alcohol to no more than one drink for women and potentially two drinks for men.

Allow yourself to have some of your favorite treats in moderation, eating them slowly and savoring each bite.

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#Thanksgiving #meal #tips

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November Blog: Tackling the Challenges of Traveling with Diabetes

Guest Contributor: Bethany Taylor

It’s that time of year again! With Thanksgiving, Christmas, and New Year’s right around the corner, many of us will be hitting the road, the airway’s, or maybe even a cruise to spend time with family and loved ones to celebrate all we have to be thankful for. Traveling within itself can be a challenge, but especially when traveling with diabetes.

A dear friend of mine with type 1 diabetes has had a few close calls when flying to some Thanksgiving destinations.  She and her husband were traveling to New York City.  She was prepared with her cool pouch for insulin vials, bag with insulin pump supplies and syringes (in case of a malfunction with the pump) and her glucose tabs.  She realized as soon as she got in the security line that she had forgotten her letter from her provider regarding her need to have insulin and insulin pump supplies due to having type 1 diabetes. She began to panic but her husband calmed her down. She explained her situation to the TSA agent who appreciated and understood her situation.  She remembered to avoid the “scanner” as it would fry her insulin pump. Disaster averted and fun time in New York City was had.

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Here are a few tips to help traveling with diabetes go more smoothly.

First, here’s a few helpful tips with air travel:

  • Make sure to share with the TSA luggage inspector you are a person with diabetes.
  • Store your medications in your carry-on bag instead of putting them in your checked bag and carry a letter with you from your prescriber describing the need for your diabetes supplies as well as a list of medications you are on to prevent any issues with security. Storing medications in your carry on also avoids the potential of them getting lost if your checked luggage gets misplaced.
  • Liquid medications can be over 3.4 ounces (100 mL) in a carry-on bag, but you need to inform the TSA screener if any are more than 100 mL.
  • When traveling across time-zones, be sure to see your prescriber four to six weeks before you travel. When you travel east, the day is shorter so you may need less insulin or may need more insulin if you travel west. You also need to check your sugar more often. If you travel from north to south or vice versa, you likely won’t need to change how you take your insulin. With oral medications such as metformin, timing isn’t as critical, but you may need to skip the second dose of a twice-daily dosing when traveling east to avoid hypoglycemia.
  • When packing, be sure to include food and supplies to prevent and treat hypoglycemia.
  • Check feet daily for pressure sores.
  • The CDC recommends that patients check their blood glucose every 4 to 6 hours during air travel.
  • Persons with diabetes using insulin pumps may request a full body pat-down or visual inspection instead of going through a metal detector.
  • The recommended vaccines for diabetes patients to receive are influenza, pneumococcal, and hepatitis B vaccines. This is something that should be addressed when visiting your doctor 4 to 6 weeks before travel.

If you are planning to do a road trip to your destination, a diabetes kit is essential. The kit should include a glucose monitor with extra batteries, a backup monitor for emergencies, plenty of lancets, and a pack of alcohol/cleaning wipes. The kit should be easily accessible but avoid putting it in the glove compartment so that it doesn’t get too hot/cold. If you take insulin, be sure to put it in a cooling pack.

Whether you’re traveling in the air or on the road, remember to visit your doctor ahead of time, prepare your supplies, and wear a diabetes medical alert bracelet in case of an emergency. Enjoy the holidays and safe travel!

Resources:

Center, Therapeutic Research. “Travel and Your Medicines.” Pharmacist’s Letter, July 2016, pharmacist.therapeuticresearch.com/Content/Segments/PRL/2016/Jul/Travel-and-Your-Medicines-9921.

“Travelers’ Health.” Centers for Disease Control and Prevention, Centers for Disease Control and Prevention, wwwnc.cdc.gov/travel/yellowbook/2020/travelers-with-additional-considerations/travelers-with-chronic-illnesses#table503.

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#tackling #travel #diabetes

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Saturday’s Daily Piece: Celebrating National Diabetes Month

Beyond Type 1 Diabetes has a special campaign during this November, National Diabetes Month. Making an invisible disease visible (#THEDROPSPOTTED). If you have Type diabetes, or a friend or family member of Type 1 diabetes, please learn more about Beyond Type 1.


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#BeyondType1 #THEDROPSPOTTED

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Thursday’s Daily Piece: Walgreens New Option CGM Access

Because CGM is billed through Medicare Part B, historically, there have been limited pharmacies providing CGM access. Walgreens has discovered the secret sauce for billing for Dexcom’s G6 CGM so now folks can have their prescription for G6 CGM filled at their local Walgreens pharmacy. Walgreens is currently working other CGM manufacturers to have ability to fill prescription for those CGMs. Always great to have options.

https://drugstorenews.com/walgreens-debuts-medicare-billing-solution-enable-cgm-access

Dexcom G6 Transmitter
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#Dexcom #G6 #Walgreens #Access

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October Blog: Coming to a Pharmacy Near You – A New Severe Hypoglycemia Treatment

Guest Contributors: Lashonta Luvene, Victoria Oshunkentan

Recently, FDA approved Gvoke HypoPenÔ, a ‘ready to use’ glucagon injection pen for the treatment of dangerously low blood sugar. Sounds interesting, so let’s jump in and gain some awareness on this new cutting edge drug! Who makes this drug? Gvoke HypoPen™ is manufactured by Xeris Pharmaceuticals. It is a pre-filled syringe that contains a room temperature, liquid-stable form of glucagon. The drug is auto-injected when pressed against the body, very similar to how an EpiPen works to treat severe allergic reactions. This medication can be used in individuals > age of 2 with type 1 or type 2 diabetes.

What exactly does glucagon do in our body? The glucagon works to quickly increase the blood sugar by signaling the liver to release its stored sugar into your bloodstream. For years, the challenge has been the glucagon emergency kit requirement of mixing powder and liquid. Imagine how difficult it would be to mix with increased adrenaline pumping in your body as you see a loved one or a friend lying on the ground with low blood sugar. With Gvoke HypoPen™, the intimidation of mixing drugs and making potential mistakes is gone!

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Things to know:

  • Available in two doses: (1) 0.5 mg/0.1 mL single-dose for pediatric patients (2) 1 mg/0.2 mL single-dose for adolescents and adults
  • Dosage forms: Gvoke HypoPenÔ (auto injector) and GvokeÔ pre-filled syringe (PFS)
  • Retail cost: $280.80 cash price per syringe
  • Administered by subcutaneous injection into lower abdomen, outer thigh, or outer upper arm

Here are just a few reasons Gvoke is so great:

  • Ready-to-use auto injector
  • Easy to manage
  • No refrigeration required
  • Can be stored at room temperature
  • Has shelf life of two years
  • Available in 2 doses for adults and kids
  • Comes in either a single pack or in a convenient 2-pack
  • Packaging allows you to keep one on hand and the other at home, school, or work.

The Gvoke HypoPen™ will be released at some point in 2020 while Gvoke™ PFS is available now. If interested in this medication, speak to your healthcare provider. Insurance coverage has not yet been announced. However, Xeris Pharmaceuticals plans to launch a co-pay assistance program to enable out-of-pocket costs ranging from roughly $0-$40 for a pack of two.

https://investors.xerispharma.com/news-releases/news-release-details/xeris-pharmaceuticals-receives-us-fda-approval-gvoketm-glucagon

https://www.xerispharma.com/about/products

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#Xeris #Gvoke #hypoglycemia

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Tuesday’s Daily Piece: Removing the Scary from Halloween Candy

I have been pondering this week what to post to encourage people living with diabetes as halloween is celebrated this week. Candy is not the forbidden evil of halloween. Rather, it can be enjoyed in moderation (1 – 2 piece of small candy (most halloween candy comes in smaller size anyway) each day). After reading a great article in diaTribe regarding halloween candy, I felt compelled to share it. Also, a shameless plug to subscribe to diaTribe if you do not already subscribe.

https://diatribe.org/issues/37/logbook?utm_source=diaTribe&utm_campaign=a9ddd88079-EMAIL_CAMPAIGN_2019_10_24_06_18&utm_medium=email&utm_term=0_22467a8528-a9ddd88079-152660205

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#halloween #candy #diabetes

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Saturday’s Daily Piece: SGLT2 Inhibitor vs. GLP1 Agonist When Have Type 2 Diabetes and Heart Disease

In a person with type 2 diabetes and heart (cardiovascular) disease, it can be a tough choice as to whether to select SGLT2 inhibitor (empagliglozin, canagliflozin, dapagliflozin) or GLP-1 agonist (liraglutide, semaglutide, albiglutide) usually after starting or when starting metformin. I list these specific drugs within each of the two drug classes because they have been studied for their benefit heart disease and diabetes.

Favor SGLT2 inhibitor if person has heart failure; fear of needles and prefers oral medication; chronic kidney disease with eGFR (measures how the kidneys can filter the blood) >45 ml/min/1.73m2.

Caution or avoidance of SGLT2 inhibitor if person has a high risk for amputation; peripheral arterial disease (blood flow in legs and feet are not so good); history of diabetic ketoacidosis; osteoporosis or at risk of falls

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Favor GLP1 agonist if person is at risk for stroke or heart attack without a history of heart failure; peripheral arterial disease with ulcer, infection or prior amputation ; obesity

Caution or avoidance of GLP1 agonist if person has had a prior gastric surgery or known gastroparesis (because this class of drugs works in the stomach); eGFR <30 ml/min/1.73 m2 (kidney is not really able to do very well with filtering the blood) or end stage kidney disease; history of medullary thyroid cancer (or MEN2); diabetic proliferative retinopathy.

Image result for glp-1 agonist cardiovascular benefit

Reference: Dhinsa DS, Mehta A, Sandesara PB, et al. Strategie for Appropriate Selection of SGLT2-i vs GLP1-RA in Persons with Diabetes and Cardiovascular Disease. Current Cardiology Reports (2019). 21:100. doi.org/10.1001/s11886-019-1197-6.

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#Diabetes #Heart #SGLT2-inhibitor #GLP-1-agonist

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Thursday’s Daily Piece: Exciting New Updates on Fiasp and Farxiga

Well, it is another exciting week in the world of diabetes. First, more rapid acting insulin aspart (Fiasp) now has expanded FDA indication for use in insulin pumps.

https://www.medscape.com/viewarticle/920162?nlid=132222_3901&src=wnl_newsalrt_191022_MSCPEDIT&uac=293412PG&impID=2139522&faf=1

Secondly, dapaglifozin (Farxiga) is now first medication indicated for treatment of Type 2 diabetes that is approved to reduce risk of heart failure hospitalization in adults with type 2 diabetes and established cardiovascular (heart) disease or multiple risk factors for heart disease. The data from the Dapagliflozin Effect on Cardiovascular Events-TIMI 58 (DECLARE-TIMI 58) trial led to this new approved indication. Please do keep in mind that in general the SGLT2 inhibitor drug class (class effect) has shown benefit for persons with type 2 diabetes and heart failure.

https://www.medpagetoday.com/cardiology/chf/82845?xid=nl_mpt_SREndocrinology_2019-10-22&eun=g1137305d0r&utm_source=Sailthru&utm_medium=email&utm_campaign=EndoUpdate_102219&utm_term=NL_Spec_Endocrinology_Update_Active

https://univadis.com/player/yqzsqyhmi/alist_nlts_1571907600727?m=unv_eml_essentials_enl_v5-q3-2019-newsrndm_20191024&partner=unl&rgid=5xzzntsmvumvuucxuzefqyb&ts=2019102400&o=tile_1_id&utm_source=Retention&utm_medium=newsletter&utm_campaign=unv_eml_essentials_enl_v5-q3-2019-newsrndm_20191024_01

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#Fiasp #FDA #Farxiga #HF

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