A rare potentially fatal infection of the perineum, fournier gangrene, is associated with sodium-glucose cotransporter-2 (SGLT-2) inhibitors. Dr. Bersoff-Matcha published a review of 55 cases reported to FDA Adverse Event Reporting System through January 2019. A SGLT-2 inhibitor class label warning for fournier gangrene has been in place since mid 2018. To learn about this review, please click below.
https://www.medscape.com/viewarticle/912634?src=wnl_edit_tpal&uac=293412PG&impID=1957647&faf=1#vp_1
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