Daily Insulin: Shorting Acting Insulin Analogues Versus Regular Human Insulin in Type 2 Diabetes

I will be highlighting insulin for my next couple of Daily Pieces as my heart aches and is heavy for those who have died from a lack of insulin. Fullerton published in Cochrane Database System Review a review of short-acting insulin analogues versus regular human insulin for adult, non-pregnant persons with Type 2 diabetes mellitus. Ten randomized controlled trials met the criteria. The authors’ conclusion, “our analysis found no clear benefits of short acting insulin analogues over regular insulin in people with type 2 diabetes. Overall, the certainty of evidence was poor and patient-relevant outcomes were sparse.” Bottom line: regular human insulin is a viable option especially when cost is an issue. The link to the review is below.


No person should die from a lack of insulin – Relion R insulin (available at Walmart for $25/vial) is an alternative to short acting insulin analogues and Relion NPH insulin (available at Walmart for $25/vial) is an alternative to basal insulin analogues especially if cost is an issue.

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